Phythochemical screening and antimicrobial activity phythochemical of essential oil from Lippia gracillis
AUTOR(ES)
Bitu, Vanessa, Botelho, Marco Antônio, Costa, José G. M. da, Rodrigues, Fabiola F. G., Veras, Helenicy N. H., Martins, Karine T., Lyra, Aarão, Coluchi, Giselle Gasparino, Ruela, Ronaldo Sousa, Queiroz, Dinalva Brito, Siqueira, Jullyana de Souza, Quintans-Junior, Lucindo J.
FONTE
Revista Brasileira de Farmacognosia
DATA DE PUBLICAÇÃO
23/09/2011
RESUMO
The chemical composition of the essential oil obtained from the fresh and dried leaves of Lippia gracillis Schauer, Verbenaceae, was analyzed by gas chromatography and gas chromatography/mass spectrometry (GC⁄MS). The yield of essential oil extracted from the dried leaves was significantly higher (p<0.05) when compared to the fresh leaves. Seventeen components were identified. The monoterpenes and sesquiterpene hydrocarbons with 96.26% (w/w) of the total oil obtained of fresh leaves and 86.99% (w/w) of the total oil obtained of dried leaves were the principal compound groups. Thymol was observed dominant (44.42%; 21.3%), followed by carvacrol (22.21%; 21.30%), p-cymene (6.23%; 8.58%), α-pinene (5.65%; 19.42%), β-caryophyllene (5.61%; 3.57%) and other minor constitutes, respectively. Microbiological results obtained by agar diffusion method, micro dilution method and minimum inhibitory concentration (MIC) showed that the essential oil has a relevant antimicrobial activity against E. coli (ATCC 10536), E. coli (Ec 27), Pseudomonas aeruginosa (ATCC 15442), S. aureus (ATCC 12692) and S. aureus (Sa 358), with their inhibition zones ranging from 9 to 13 mm and the MIC ranging from 64 to 512 μg/mL.
Documentos Relacionados
- Antimicrobial activity of the essential oil from Lippia sidoides, carvacrol and thymol against oral pathogens
- Antioxidant capacity and larvicidal activity of essential oil and extracts from Lippia grandis
- Antimicrobial action of the essential oil of Lippia gracilis Schauer
- Composition, anti-quorum sensing and antimicrobial activity of essential oils from Lippia alba
- Composition and antimicrobial activity of the essential oil from Aloysia sellowii