Phage-induced changes in Vibrio cholerae: serotype and biotype conversions.
AUTOR(ES)
Ogg, J E
RESUMO
Phage infection of Vibrio cholerae resulted in antigenic changes. A strain of biotype cholerae serotype Ogawa was converted into serotype Hikojima and gained the ability to synthesize antigenic factor C. Some phage-converted strains remained stable after subculture and were immune to superinfection with the same phage. The stable converted strains were lysogenic and released phage having a host range similar to the phage of the donor strain. Reinfection of unstable converted strains which had "lost" antigen C yielded types able to again synthesize this antigen. The polymyxin resistance character was expressed in the biotype cholerae strain after infection with some phage preparations. These polymyxin-resistant strains possessed three main characteristics of El Tor vibrios. The phage-induced changes described provide V. cholerae with the potential for innumerable genetic combinations.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=414072Documentos Relacionados
- CTX Prophages in Classical Biotype Vibrio cholerae: Functional Phage Genes but Dysfunctional Phage Genomes
- Antigenic changes in Vibrio cholerae biotype eltor serotype Ogawa after bacteriophage infection.
- ENZYMATIC PROPERTIES OF A PHAGE-INDUCED LYSIN AFFECTING GROUP A STREPTOCOCCI
- The enzymatic repair of DNA, II. Characterization of phage-induced sealase.
- The Selective Inhibition of Protein Initiation by T4 Phage-Induced Factors