Perfil de alterações cognitivas em pacientes com fibrose pulmonar idiopática / Cognitive impairment profile of patients with idiopathic pulmonary fibrosis

AUTOR(ES)

Renata Areza Fegyveres

DATA DE PUBLICAÇÃO

2009

RESUMO

Background: Lung disease with hypoxaemia as chronic pulmonary obstructive disease may be associated with cognitive impairment caused by continuous fall in oxygen saturation. Objective: 1) to identity if there is cognitive impairment in patients with idiopathic pulmonary fibrosis; 2) if present, to evaluate the neuropsychological profile of these alterations and 3) to verify if there is correlation of disease severity and cognitive performance. Methods: Twenty-one patients with idiopathic pulmonary fibrosis were selected from the Interstitial Lung disease Out-patient Clinic and were submitted throughout conventional neurological exam, blood lab, neuroimaging, broad neuropsychological and lung function evaluation. The control group consisted of twenty non-demented healthy subjects paired by gender, age, schooling and socio-economic level. Results: The Mini-mental state examination, Semantic verbal fluency (fruit category), learning item of the Brief Cognitive Battery, Digit symbol test and Trail making part B results were different between both groups (p <0.05). Conclusions: This study showed that patients with IPF performed worse in tests of executive functions and mental speed, which is congruent with the hypotheses of encephalopathy of subcortical type similar to the one found in patients with other lung hypoxaemic disease. These results should be confirmed with more accurate reaction time tests

ASSUNTO(S)

cognição anoxia anóxia cognition testes neuropsicológicos lung fibrosis neuropsychological tests fibrose pulmonar

Documentos Relacionados

• Fibrose pulmonar idiopática simultânea a enfisema em pacientes tabagistas = Idiopathic pulmonary fibrosis and enphysema in smokers
• Microbiological profile of cystic fibrosis patients
• Effects of proportional assist ventilation on exercise capacity in idiopathic pulmonary fibrosis patients
• Quantificação das alterações vasculares pulmonares na fibrose pulmonar idiopática e suas implicações prognósticas
• Avaliação funcional pulmonar em pacientes com fibrose pulmonar idiopática submetidos a transplante pulmonar