PcrV Immunization Enhances Survival of Burned Pseudomonas aeruginosa-Infected Mice
AUTOR(ES)
Holder, Ian Alan
FONTE
American Society for Microbiology
RESUMO
Burned Pseudomonas aeruginosa-infected mice immunized against PcrV, a type III virulence system translocating protein, showed significantly enhanced survival compared to controls. Survival was non-O serotype specific and correlated with a reduced systemic microbial load. Infection with a high-level toxin A-producing strain required supplemental antitoxin treatment to enhance survival.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=98711Documentos Relacionados
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