Parameters indicative of absorption and biological effect in new lead exposure: a prospective study

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Tola, S., Hernberg, S., Asp, S., and Nikkanen, J. (1973).British Journal of Industrial Medicine,30, 134-141. Parameters indicative of absorption and biological effect in new lead exposure: a prospective study. Determinations have been made of the blood and urinary lead concentrations (Pb-B, Pb-U), haemoglobin concentrations (Hb), packed blood cell volumes (Hcr), urinary δ-aminolevulinic acid (ALA-U) and coproporphyrin concentrations (CP-U), as well as erythrocyte δ-aminolevulinic acid dehydratase activities (ALA-D), in respect of 33 workers entering occupational lead exposure for the first time in their lives. In a follow-up study lasting from one to four months samples were taken before exposure began, initially at intervals of two days and subsequently at intervals of one to two weeks. Nine control subjects were studied for Pb-B once, and for Hb, Hcr, and ALA-D weekly.

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