On the unknown ecological niche of Paracoccidioides brasiliensis: our hypothesis of 1989: present status and perspectives
AUTOR(ES)
Conti Días, Ismael A.
FONTE
Revista do Instituto de Medicina Tropical de São Paulo
DATA DE PUBLICAÇÃO
2007-04
RESUMO
In 1989, CONTI DÍAZ & RILLA published a hypothesis concerning the as yet unknown ecological niche of Paracoccidioides brasiliensis. The hypothesis proposed a highly efficient paracoccidioidal ecological strategy based on an important natural reservoir of the parasite, probably in heterothermic animals from fresh water environments. Further, the hypothesis proposed, a transient and variable residence in the soil with a wide aleuriospore dispersion throughout the environment together with an elevated capability of infecting humans, and domestic and wild animals. This paper analyzes scientific publications from the IX International Meeting on Paracoccidioidomycosis held in Águas de Lindoia, São Paulo, Brazil from 2-5 October 2005, providing a comparative study among this articles and with other recently published papers and the hypothesis' postulates. Since various findings and observations appear to agree with the postulates, the pursuit of novel, specific research projects in the supposed reservoirs is recommended partially or fully to confirm the hypothesis using classical laboratorial methods and modern molecular biology techniques.
Documentos Relacionados
- Cryptic species of Paracoccidioides brasiliensis: impact on paracoccidioidomycosis immunodiagnosis
- Fungal Colitis by Paracoccidioides brasiliensis: a case report
- Exocellular components of Paracoccidioides brasiliensis: identification of a specific antigen.
- Paracoccidioides brasiliensis: Conversion of Yeastlike Forms into Mycelia in Submerged Culture
- Preferential transcription of Paracoccidioides brasiliensis genes: host niche and time-dependent expression