N-METHYL GROUPS IN BACTERIAL LIPIDS
AUTOR(ES)
Goldfine, Howard
RESUMO
Goldfine, Howard (Harvard Medical School, Boston, Mass.), and Martha E. Ellis. N-methyl groups in bacterial lipids. J. Bacteriol. 87:8–15. 1964.—The ability of bacteria to synthesize lecithin was examined by measuring the incorporation of the methyl group of methionine into the water-soluble moieties obtained on acid hydrolysis of bacterial lipids. Of 21 species examined, mostly of the order Eubacteriales, only 2, Agrobacterium radiobacter and A. rhizogenes, incorporated the methyl group of methionine into lipid-bound choline. Evidence was also obtained for the formation of lipid-bound N-methylethanolamine and N,N′-dimethylethanolamine in these two organisms. Two other species, Clostridium butyricum and Proteus vulgaris, incorporated the methyl group of methionine into lipid-bound N-methylethanolamine, but did not appear to be able to further methylate these lipids to form lecithin. The results of this study lend further strength to the generalization that bacteria, with the exception of the genus Agrobacterium, are unable to synthesize lecithin.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=276954Documentos Relacionados
- N-Methyl Groups in Bacterial Lipids III. Phospholipids of Hyphomicrobia
- Blood-brain barrier penetration abolished by N-methyl quaternization of nicotine.
- N-methyl aspartate activates voltage-dependent calcium conductance in rat hippocampal pyramidal cells.
- Stimulation of Methanogenesis by Aldicarb and Several Other N-Methyl Carbamate Pesticides †
- Utilization of trimethylamine and other N-methyl compounds for growth and methane formation by Methanosarcina barkeri.
