Metabolic evidence of vitamin B-12 deficiency, including high homocysteine and methylmalonic acid and low holotranscobalamin, is more pronounced in older adults with elevated plasma folate123
AUTOR(ES)
Miller, Joshua W
FONTE
American Society for Nutrition
RESUMO
Background: An analysis of data from the National Health and Nutrition Examination Survey indicated that in older adults exposed to folic acid fortification, the combination of low serum vitamin B-12 and elevated folate is associated with higher concentrations of homocysteine and methylmalonic acid and higher odds ratios for cognitive impairment and anemia than the combination of low vitamin B-12 and nonelevated folate. These findings await confirmation in other populations.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2777470Documentos Relacionados
- Folate and vitamin B-12 and risk of fatal cardiovascular disease: cohort study from Busselton, Western Australia
- The electroencephalogram in veganism, vegetarianism, vitamin B12 deficiency, and in controls.
- Anaemia in rheumatoid arthritis: the role of iron, vitamin B12, and folic acid deficiency, and erythropoietin responsiveness.
- Regulation of 5-Methyltetrahydrofolate:Homocysteine Methyltransferase Activity by Methionine, Vitamin B12, and Folate in Cultured
- Production of vitamin B-12 in tempeh, a fermented soybean food.