Mechanisms involved in the vasorelaxant effects produced by the acute application of amfepramone in vitro to rat aortic rings
AUTOR(ES)
López-Canales, J.S., Lozano-Cuenca, J., Muãoz-Islas, E., Aguilar-Carrasco, J.C., López-Canales, O.A., López-Mayorga, R.M., Castillo-Henkel, E.F., Valencia-Hernández, I., Castillo-Henkel, C.
FONTE
Braz J Med Biol Res
DATA DE PUBLICAÇÃO
27/03/2015
RESUMO
Amfepramone (diethylpropion) is an appetite-suppressant drug used for the treatment of overweight and obesity. It has been suggested that the systemic and central activity of amfepramone produces cardiovascular effects such as transient ischemic attacks and primary pulmonary hypertension. However, it is not known whether amfepramone produces immediate vascular effects when applied
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