Is there a place for N-acetylcysteine in the treatment of septic shock?

AUTOR(ES)

Del Sorbo, Lorenzo

FONTE

BioMed Central

RESUMO

Excessive inflammatory responses and impaired oxygen utilization because of microcirculatory failure are implicated in septic shock. Recent studies have pointed out some beneficial effects in the treatment of septic shock of several vasodilators that exert anti-inflammatory properties. In particular, the antioxidant N-acetylcysteine has been demonstrated to enhance cardiac performance, and to improve hepatosplanchnic perfusion and liver function in patients with established septic shock. These clinical observations may lead us to examine further the role of antioxidant agents in developing novel therapies for septic shock.

Documentos Relacionados

• N-acetylcysteine in the treatment of skin-picking disorder
• Systematic review of N-acetylcysteine in the treatment of addictions
• Trichotillomania: a good response to treatment with N-acetylcysteine
• Oral N‐acetylcysteine for acute paracetamol poisoning
• N-acetylcysteine as an adjunctive treatment for smoking cessation: a randomized clinical trial