Inhibition of Neutrophil Apoptosis by Verotoxin 2 Derived from Escherichia coli O157:H7
AUTOR(ES)
Liu, Jiajia
FONTE
American Society for Microbiology
RESUMO
In order to evaluate the pathological role of verotoxin 2 (VT2), we investigated the effects of VT2 on neutrophil apoptosis in vitro. The results showed that VT2 caused a significant delay in spontaneous neutrophil apoptosis and that the effect was abrogated by a protein kinase C inhibitor. These data indicate that longer survival of neutrophils may aggravate neutrophil-mediated tissue damage in VT2-associated diseases.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=97017Documentos Relacionados
- Multiple determinants of verotoxin-producing Escherichia coli O157:H7 attachment-effacement.
- Inhibition of Escherichia coli serotype O157:H7 by bromthymol blue.
- Detection and production of verotoxin 1 of Escherichia coli O157:H7 in food.
- Escherichia coli O157:H7
- Loss of O157 O Antigenicity of Verotoxin-Producing Escherichia coli O157:H7 Surviving under Starvation Conditions
