Inactivation of Encephalomyocarditis Virus in Aerosols: Fate of Virus Protein and Ribonucleic Acid
AUTOR(ES)
De Jong, J. C.
RESUMO
After aerosolization at relative humidities of 50% or lower, encephalomyocarditis virus is rapidly inactivated. In this process the protein coat of the virion is damaged. This appears as a loss of hemagglutination activity and loss of affinity for hemagglutination inhibiting antibodies. The ribonucleic acid of the virus retains its infectivity but it becomes susceptible to ribonuclease. It sediments in sucrose gradients when centrifuged at high speed with the same velocity as free infectious ribonucleic acid extracted with phenol from intact encephalomyocarditis virus.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=379968Documentos Relacionados
- Factors in the inactivation of Encephalomyocarditis virus in aerosols.
- Intracellular Fate of Mengo Virus Ribonucleic Acid
- Simple Method for the Isolation of Encephalomyocarditis Virus Ribonucleic Acid
- Virus Protein Synthesis in Animal Cell-Free Systems: Nature of the Products Synthesized in Response to Ribonucleic Acid of Encephalomyocarditis Virus
- Inactivation of Baceriophage T3 in Aerosols: Effect of Prehumidification on Survival After Spraying from Solutions of Salt, Peptone, and Saliva
