High-Level Production of Heterologous Protein by Engineered Yeasts Grown in Cottage Cheese Whey

AUTOR(ES)

Maullu, Carlo

FONTE

American Society for Microbiology

RESUMO

Cottage cheese whey is a cheese industry by-product still rich in proteins and lactose. Its recycling is seldom cost-effective. In this work we show that the lactose-utilizing yeast Kluyveromyces lactis, engineered for production of recombinant human lysozyme, can be grown in cottage cheese whey, resulting in high-level production of the heterologous protein (125 μg/ml).

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