Herpes simplex virus infection in guinea pigs: an animal model for studying latent and recurrent herpes simplex virus infection.
AUTOR(ES)
Scriba, M
RESUMO
Footpad infection of guinea pigs with herpes simplex virus led to an acute local inflammatory reaction, followed by a persistent latent infection of lumbosacral dorsal root ganglia. Spontaneous reactivation of the latent virus occurred, leading to recurrent lesions at the site of the initial infection. Clinical observations and virological studies during the acute latent and recurrent infection are reported.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=415261Documentos Relacionados
- Cryptosporidiosis in guinea pigs: an animal model.
- Pathogenesis of latent herpes simplex virus infection of the trigeminal ganglion in guinea pigs: effects of age, passive immunization, and hydrocortisone.
- Role of antibody in primary and recurrent herpes simplex virus infection.
- Psychosocial implications of recurrent genital herpes simplex virus infection.
- Regulation by recombinant interleukin-2 of protective immunity against recurrent herpes simplex virus type 2 genital infection in guinea pigs.
