Genome-wide analysis of protein-DNA interactions in living cells

AUTOR(ES)

Pugh, B Franklin

FONTE

BioMed Central

RESUMO

Understanding the regulation of gene expression requires an analysis of gene-specific transcription factors. This review highlights recent work that uses protein-DNA crosslinking, immunoprecipitation and DNA microarrays to determine the binding sites for specific transcription factors throughout the yeast genome.

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