First secondary metabolites from Herissantia crispa L (Brizicky) and the toxicity activity against Artemia salina Leach

Costa, Danielly Albuquerque da, Matias, Wemerson Neves, Lima, Igara Oliveira, Xavier, Aline Lira, Costa, Vivian Bruna Machado, Diniz, Margareth de Fátima Formiga Melo, Agra, Maria de Fátima, Batista, Leônia Maria, Souza, Maria de Fátima Vanderlei de, Silva, Davi Antas e

First secondary metabolites from Herissantia crispa L (Brizicky) and the toxicity activity against Artemia salina Leach

AUTOR(ES)

Costa, Danielly Albuquerque da, Matias, Wemerson Neves, Lima, Igara Oliveira, Xavier, Aline Lira, Costa, Vivian Bruna Machado, Diniz, Margareth de Fátima Formiga Melo, Agra, Maria de Fátima, Batista, Leônia Maria, Souza, Maria de Fátima Vanderlei de, Silva, Davi Antas e

FONTE

Química Nova

DATA DE PUBLICAÇÃO

2009

RESUMO

The phytochemical investigation of Herissantia crispa led to the isolation of seven compounds, identified as: sitosterol 3-O-β-D-glucopyranoside, stigmasterol 3-O-β-D-glucopyranoside, 3,5,7,4'-tetrahydroxyflavone (kaempferol), 3,5,7,3',4'-pentahydroxyflavone (quercetin), unpublished in the genus Herissantia, besides β-sitosterol, kaempferol 3-O-β-D-(6''-E-p-coumaroil) (tiliroside) glucopyranoside and kaempferol 3,7-di-O-α-L-ramnopyranoside (lespedin), described for the first time in the species. The structural determination of the compounds was made by means of spectroscopy methods such as Infrared Spectroscopy, ¹H and 13C Nuclear Magnetic Resonance, with the aid of two dimensional techniques, and by comparison with literature data. The toxicity activity of the MeOH extract and lespedin on Artemia salina Leach. was also carried out.