Fascia grafting in the lamina propria of vocal folds : an histological experimental study / Integração de fragmento de fascia lata enxertado na lamina propria de prega vocal de cães : estudo histologico

AUTOR(ES)
DATA DE PUBLICAÇÃO

2006

RESUMO

Satisfactory corrective treatment for sulcus, scar and senile alterations in the lamina propria of vocal folds is still under development. This study assessed the utilization of a fascia lata graft in the vocal fold lamina propria of dogs by analyzing the histological alterations induced by acute and chronic inflammatory reactions as well as the fibrosis triggered by graft procedure and persistence. A fragment measuring 0.3 X 0.3 cm of the fascia lata was grafted in the right vocal old lamina propria of 12 adult dogs. Identical surgical access in the left vocal fold was reproduced without introducing the graft. After periods of two and six months, the animals were sacrificed and a histological study of their vocal cords was performed. Besides the reactions resulting from the surgical procedure in the control side, the fascia did not induce an acute or chronic inflammatory reaction or trigger fibrosis in any of the animals. In all the cases, the grafted tissue did not show evidence of resorption, demonstrating that the superficial layer of the lamina propria in dogs presents good tolerance to fascia lata grafting.

ASSUNTO(S)

cordas vocais fascia lata extracellular matrix matriz extracelular vocal cords autologous transplantation transplante autologo fascia lata

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