EXPERIMENTO DIDÁTICO DE QUIMIOMETRIA PARA O MAPEAMENTO DE PELLETS FARMACÊUTICOS UTILIZANDO ESPECTROSCOPIA DE IMAGEM NA REGIÃO DO INFRAVERMELHO PRÓXIMO E RESOLUÇÃO MULTIVARIADA DE CURVAS COM MÍNIMOS QUADRADOS ALTERNANTES: UM TUTORIAL, PARTE IV

AUTOR(ES)
FONTE

Quím. Nova

DATA DE PUBLICAÇÃO

2018-03

RESUMO

The aim of this manuscript is to present a didactic experiment based on the combination of Near Infrared chemical imaging and Multivariate Curve Resolution for beginners, undergraduate and graduate students. In this tutorial, using MATLAB environment, the instrumental signals will be separated into two matrices, of spectral profiles and relative concentrations in the samples. Then, chemical images were generated to identify and verify the distribution of the components in the pellet samples. Chemical imaging was obtained from the mapping of predetermined area and the results for relative concentrations obtained in the ALS optimization for the analyzed area. This approach was successfully tested in chemistry undergraduate course at the Chemistry Institute of Campinas State University.

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