Evaluation of different media for the production of cephalosporins by Streptomyces clavuligerus ATCC 27064

AUTOR(ES)

Antonio, Tatiana, Bellão, Carolina, Corrêa, Tatiana, Cavallieri, André Pastrelo, Badino, Alberto Colli, Araujo, Maria Lucia Gonsales da Costa

FONTE

Braz. arch. biol. technol.

DATA DE PUBLICAÇÃO

2012-12

RESUMO

The aim of this work was to compare the composition of a complex and soluble culture medium to eight other media described in the literature through the batch cultivation in a conventional bench-scale bioreactor for the production of cephamycin C by a wild strain of Streptomyces clavuligerus. The proposed medium resulted in an antibiotic production 1.5 to 7.5 times higher than the other culture media.

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