"Estudo da utilização clínica das proteínas ósseas morfogenéticas em cirurgia buco-maxilo-facial no Brasil" / Study of the use of Bone Morphogenetic Proteins in Cranio-maxillo- facial Surgery in Brazil.

AUTOR(ES)

Alessandra Arnaud Moreira

DATA DE PUBLICAÇÃO

2004

RESUMO

The use of alloplastic materials for bone replacement has been extensively debated lately by surgeons and researchers in the Oral and Maxillofacial field. In the attempt to reconstruct bone defects anatomically and functionally autogenous bone grafts have been the preferred option. Although being considered the gold standard in craniofacial reconstruction, there are some inconveniences in the use of bone autografts. Among them the need of hospitalization, the need of a donor site usually in a different area than the bone defect, donor area morbidity, longer recovery time, increased risk of infection, and the possibility of bone resorption over time. When the face is operated the use of autogenous bone is even more questionable. Usually small amounts of bone grafts are necessary in the face, and might not justify the morbidity of the donor site. In an attempt to avoid the use of bone autografts, allografts and alloplastic materials have been advertised, in association with bone morphogenetic proteins. These proteins are growth factors involved in the osteogenesis in humans from the fetus up to the adult age. The aim of this study is to evaluate the knowledge and the clinical use of bone morphogenetic proteins in the repair of facial bone defects by Brazilian Oral and Maxillofacial surgeons.

ASSUNTO(S)

ossos faciais bone transplant growth factors bone regeneration facial bones regeneração Óssea transplante Ósseo substância de crescimento

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