Estudo da fertilidade em pacientes lupicas

AUTOR(ES)
DATA DE PUBLICAÇÃO

1993

RESUMO

Although a large proportion of patients with systemic lupus erythemathosus (SLE) are women of reproductive age, aclear picture of the effects of the disease on pregnancy and vice versa was slow to emerge. The initial small retrospective studies of this interaction yielded conflicting results. Confounding factors were the lack of agreed criteria for the diagnosis of exacerbation and the potential confusion among certain features of normal pregnancy and lupus fIare. Besides the lupus effect on fertility rate wasn t ex~lored enough. There are few studies and alI of the~out of our country. In order to study the fertility among SLE patients followed at the State University of Campinas between 1973 to 1992, and to analyse the abortions, anticardiolipin antibody (aCL) freguency and the clinical, laboratorial and therapeutic aspects importa~ce on the reproductive history of those patients,186 lupic patient,s, compared to 131 normal women, were studied retrospectively. The mean age among lupic patients was 32,77 years-old, a~d 33,98 among the controls. The number of pregnancies was lower in patients than in controls, as well as agreater number of patients that never had pregnancy than those ones controlled. Abortions were present in a higher number among the lupic patients and the difference between the groups was Statisticly significant. However, this feature was not related to the aCL positivity. There clinical management had noto were not significant differences and laboratorial features, as well as in the relation to therapeutic among the patients who had pregnancies and those who had not

ASSUNTO(S)

fecundidade lupus eritematoso

ACESSO AO ARTIGO

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