Estudo comparativo da celularidade da reação inflamatória aguda na serosa e mesentério intestinais às telas de poliamida e polipropileno em ratos wistar com peritonite fecal por técnica morfométrica

AUTOR(ES)

Ricardo Fantazzini Russi

DATA DE PUBLICAÇÃO

2004

RESUMO

Laparostomy constitutes in important strategy in the management of patients with severe acute peritonitis and compartmental abdominal syndrome. Prosthetic materials are used to close the abdominal cavity temporally and the polyamide has been little mention in medical literature. Researches are about chronic inflammatory response. However in laparostomy the prosthesis is removed until 48 hours after the last procedure and research about acute inflammatory response are necessary. Polypropylene mesh is habitually used but it is expensive. Objective. To study the acute cellular inflammatory reaction, under morphometric evaluation, of serosa and mesentery intestinal in contact with polyamide and polypropylene mesh in Wistar rats with fecal peritonitis. Methods. Sixty-seven Wistar rats were used distributed in 3 groups: 1 control, 1 sham and 1 experimental. The experimental group was distributed polypropylene - Ppe (acute peritonitis and polypropylene mesh) and polyamide experimental # Pae (acute peritonitis and polyamide mesh). The acute cellular inflammatory response was studied in the intestinal serosa and mesenteric tissue in contact with meshes in both groups with acute peritonitis and mesh. Statistical evaluation was done by Kruskal-Wallis test for multiple comparison procedures and Dunn#s method for pair comparison procedures. The null hypothesis was rejected at the 5% significance level (p<0,05). Results. There was no difference in cellular response in animals of Ppe and Pae groups. Conclusion. Data allows conclude that there is no difference in cellular response in Ppe and Pae groups and the acute peritonitis was responsible by acute cellular inflammatory response in the current research.

ASSUNTO(S)

ciencias da saude peritonite - cirurgia ciencias medicas

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