Epigenetic reprogramming in the mammalian embryo: struggle of the clones

AUTOR(ES)

Mann, Mellissa RW

FONTE

BioMed Central

RESUMO

During preimplantation development in mammals, distinct epigenetic marks on oocyte and sperm DNA are remodeled to an embryonic pattern. A recent study examining global methylation of repetitive elements in various mammals showed that the reprogramming that occurs during normal preimplantation development is aberrant in cloned embryos.

Documentos Relacionados

• Epigenetic reprogramming and induced pluripotency
• The Status of the Human Embryo: Perspectives from Moral Tradition
• Conservation of methylation reprogramming in mammalian development: Aberrant reprogramming in cloned embryos
• DNA Polymerase of Chicken Embryo: Purification and Properties*
• The human embryo: Aristotle and the Arabic and European traditions