Endothelial cell proliferation associated with lesions of murine systemic candidiasis.

AUTOR(ES)

Ashman, R B

RESUMO

Neovascularization is associated with tumor growth and some inflammatory diseases but has not been reported to be induced by infectious agents. In a mouse model of systemic Candida albicans infection, extensive endothelial cell proliferation was seen in the periphery of brain abscesses and in the areas of fungal pyelonephritis in the kidney. This finding is important for an understanding of the pathogenesis of fungal infections and may contribute to an analysis of the mechanisms of angiogenesis.

Documentos Relacionados

• Importance of beta2-microglobulin in murine resistance to mucosal and systemic candidiasis.
• Effects of cyclophosphamide on murine candidiasis.
• Antifungal agents in neonatal systemic candidiasis.
• Aspectos imunológicos e microbiológicos da candidose bucal.
• Tumor necrosis factor alpha has a protective role in a murine model of systemic candidiasis.