Effects of low intensity pulsed ultrasound irradiation on the secondary healing of a round shaped total skin lesion in rats, assessd by means of planimetry. / Efeitos do ultra-som pulsado de baixa intensidade sobre a cicatrização por segunda intenção de lesões cutâneas totais em ratos, mediante avaliação por planimetria.

AUTOR(ES)
DATA DE PUBLICAÇÃO

2005

RESUMO

The effects of low intensity pulsed ultrasound irradiation on the secondary healing of a round shaped (1 cm in diameter) total skin lesion, produced on the dorsal region of rats, were studied. Sixty male Wistar rats weighing 300 g on average were used and divided into two groups of 30 animals each, according to treatment: Group 1, simulated irradiation (control); Group 2, effective irradiation (irradiated). 1.5 MHz fundamental frequency, 1 KHz pulse repetition frequency, 200 µs pulse width, 30mW/cm2 intensity (SATA), 10 minutes application in alternate days). Each group was divided into three subgroups: 3, 7 and 14 days, according to the postoperative period of ultrasound irradiation, and healing was evaluated by means of planimetry. The healed area was significantly increased (p<0.05) in Group 2 (141.88±18.50 mm2) as compared to Group 1 (117.38±15.14 mm2) on the 14th day. No differences were observed between subgroups for the other experimental periods. The author conclude that low intensity pulsed ultrasound irradiation presented virtually no deleterious effect and moderately stimulated secondary healing of total skin lesions in the experimental conditions of this investigation, with potential for clinical application in similar situations in humans. Also, planimetry showed to be effective method in evaluating the healing of skin lesions.

ASSUNTO(S)

planimetria ultra-som de baixa intensidade planimetry total skin lesion secondary healing low intensity ultrasound cicatrização por segunda intenção lesões cutâneas totais

ACESSO AO ARTIGO

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