Effect of N′-Methylnicotinamide on the Renal Accumulation and Reabsorption of Gentamicin in Rats

AUTOR(ES)
RESUMO

N′-methylnicotinamide, a substrate of the organic base transport system, reduced renal accumulation of [14C]gentamicin in rats by 15% and increased clearance by 25%, suggesting that gentamicin is not secreted by this mechanism.

Documentos Relacionados