Dishevelled and Wnt signaling: is the nucleus the final frontier?
AUTOR(ES)
Habas, Raymond
FONTE
BioMed Central
RESUMO
The phosphoprotein Dishevelled (Dsh) is an essential component of Wnt signaling pathways and transduces signals into three separate branches, the canonical, non-canonical and Ca2+ pathways. How Dsh focuses signaling into these branches remains mysterious, but a new study reveals the importance of nuclear localization of Dsh for pathway-specific activation.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=551522Documentos Relacionados
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