Discrimination between Messenger Ribonucleic Acids by a Mammalian Translation Initiation Factor
AUTOR(ES)
Nudel, U.
RESUMO
A factor from rabbit-reticulocyte ribosome, which stimulates by 5-fold initiation of hemoglobin mRNA translation in Krebs ascites cell extracts, was purified to homogeneity. The factor, a protein of about 65,000 molecular weight in sodium dodecyl sulfate, discriminates between various mRNAs: it stimulates translation of α globin mRNA and of tobacco mosaic virus RNA, but has only a small effect on β globin mRNA and no effect at all on Mengo virus RNA translation.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=433683Documentos Relacionados
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