Dinamica de transmissão do HIV entre usuários de drogas injetáveis, na cidade de Santos, São Paulo, Brasil / Dynamic of HIV transmission among injecting drug users, in the city of Santos, Sao Paulo, Brazil

AUTOR(ES)
DATA DE PUBLICAÇÃO

1995

RESUMO

In order to study the seroprevalence of HIV and infections with related transmission patterns, as hepatitis B and C, syphilis and HTLV (1 and 2), we interviewed and bled 197 IDUs, sampled by snow-balling and compared with 197 blood donors matched for age and sex, both groups from the city of Santos, Sao Paulo, Brazil. Seroprevalences found were 62% for HIV, 75% for HCV, 75% for HBV, 34% for syphilis and 25% for HTLV (1 or 2) among IDUs, which compare with 0.0%, 2%, 23%, 12%, and 1% for blood donors, respectively. The risk for parenterally transmitted infections in this IDUs community is higher than that for sexually transmitted one. We also estimated the Basic Reproduction Ratio, R0, for HIV among IDUs. Using a model adapted from the classical Macdonalds model for vector-born infection, the R0 resulted in 28 and 98, assuming an homogeneous or heterogeneous distribution of infective inoculae, respectively. This estimation was based only on parenteral transmission. Using this model the expected equilibrium for HIV seroprevalence (0.67) is close to the observed seroprevalence (0.62)

ASSUNTO(S)

drogas ilícitas hiv infections/epidemiology abuso de substâncias por via intravenosa/sangue risk factors substance abuse intravenous/blood hiv/patogenicidade infecções por hiv/epidemiologia infecções por hiv/transmissão street drugs hiv infections/transmission fatores de risco

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