Development and Evaluation of a Rapid Dipstick Assay for Serodiagnosis of Acute Human Brucellosis

AUTOR(ES)

Smits, Henk L.

FONTE

American Society for Microbiology

RESUMO

A dipstick assay for the detection of brucella-specific immunoglobulin M antibodies was evaluated with 707 sera from 247 laboratory-confirmed brucellosis patients and 342 control sera from brucellosis-free individuals. These sera were collected from six different countries. The assay was found to be highly sensitive and specific. In addition, the test is easy to use and does not require specialized training or equipment, and the components are stable without a requirement for refrigeration. All of these factors make the test ideal for developing countries and rural settings.

Documentos Relacionados

• Comparison of a Dipstick Assay for Detection of Brucella-Specific Immunoglobulin M Antibodies with Other Tests for Serodiagnosis of Human Brucellosis
• Development and Evaluation of a PCR-Enzyme-Linked Immunosorbent Assay for Diagnosis of Human Brucellosis
• Evaluation of an Immunocapture-Agglutination Test (Brucellacapt) for Serodiagnosis of Human Brucellosis
• Lateral-Flow Assay for Rapid Serodiagnosis of Human Leptospirosis
• Simple Latex Agglutination Assay for Rapid Serodiagnosis of Human Leptospirosis