"Definição de conduta na investigação de doença coronária obstrutiva utilizando teoria de conjuntos fuzzy aplicada a dados clínico-epidemiológicos, ergométricos e cintilográficos" / Establishment of diagnostic procedures for coronary artery disease based on fuzzy set theory applied to clinical epidemiological data and treadmill electrocardiography and myocardial perfusion scintigraphy results.

AUTOR(ES)
DATA DE PUBLICAÇÃO

2004

RESUMO

Coronary artery disease (CAD) is a worldwide leading cause of death. Early detection is important to prevent such sort of outcome. The gold standard method for evaluating critical partial occlusions is coronary arteriography, a catheterization technique which is invasive, time consuming, and costly. There are noninvasive approaches for early detection of CAD. The basis for the noninvasive diagnosis of CAD has been laid in a sequential analysis of the risk factors, and the results of treadmill electrocardiography and myocardial perfusion scintigraphy. Many investigators have demonstrated that appropriate diagnostic applications of myocardial perfusion scintigraphy and coronary arteriography are in patients who have an intermediate and a high likelihood of disease, respectively. Although this information is useful, it is only partially utilized in the clinical practice due to the difficulty to properly classify the patients. Since the seminal article by Lotfi A. Zadeh fuzzy logic has been applied in numerous areas. It is especially suited to medical applications, since much of the information required for decision-making is uncertain. In this paper, we proposed and tested models to select patients that have to undergo myocardial perfusion scintigraphy and coronary arteriography based on fuzzy set theory. It was used a group of 1053 patients to develop the models and another one of 1045 patients to test them. It was utilized ROC curves to compare the performance of the models with the ones of experts’ physicians and it was observed that the fuzzy models have a performance equal or superior to the experts in the selection of the patients that should perform scintigraphy and coronary arteriography, therefore, they could be a useful tool to assist the general practitioner in this task.

ASSUNTO(S)

cineangiografia/métodos coronary disease/radionuclide imaging ergometria/métodos fuzzy logic lÓgica fuzzy physician s practice patterns cineangiography/methods condutas na prÁtica dos mÉdicos coronariopatia/cintilografia ergometry/methods

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