Conversion of Histidine to Hercynine by Neurospora crassa

AUTOR(ES)

Reinhold, Vernon N.

RESUMO

Cell-free extracts of Neurospora crassa mycelium catalyze the methylation of l-histidine to form hercynine (histidine betaine). The partially methylated compounds, α-N-methyl-l-histidine and α-N,N-dimethyl-l-histidine, are also methylated by the same enzyme preparation to form hercynine. All three methylation reactions are stimulated by the addition of S-adenosylmethionine.

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