Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene.
AUTOR(ES)
Hentze, M W
RESUMO
A genomic phage clone containing a full-length copy of a functional human gene for ferritin heavy chain has been isolated. The gene consists of four exons spanning approximately 3 kilobases and has been localized to chromosome 11. The functionality of the gene was demonstrated by the fact that both transient transfectants and stable transformants of murine fibroblasts actively transcribe human ferritin heavy-chain mRNA.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=386688Documentos Relacionados
- Cloning, characterization, and multiple chromosomal integration of a Bacillus alkaline protease gene.
- Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase.
- Molecular cloning, expression, and chromosomal localization of the gene encoding a human myeloid membrane antigen (gp150).
- Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.
- Dispersed localization of D segments in the human immunoglobulin heavy-chain locus.