Characterization of Staphylococcus aureus Enterotoxin L
AUTOR(ES)
Orwin, Paul M.
FONTE
American Society for Microbiology
RESUMO
Staphylococcus aureus causes a wide variety of diseases. Major virulence factors of this organism include enterotoxins (SEs) that cause both food poisoning and toxic shock syndrome. Recently, a novel SE, tentatively designated SEL, was identified in a pathogenicity island from a bovine mastitis isolate. The toxin had a molecular weight of 26,000 and an isoelectric point of 8.5. Recombinant SEL shared many biological activities with SEs, including superantigenicity, pyrogenicity, enhancement of endotoxin shock, and lethality in rabbits when administered in subcutaneous miniosmotic pumps, but the protein lacked emetic activity. T cells bearing the T-cell receptor β chain variable regions 5.1, 5.2, 6.7, 16, and 22 were significantly stimulated by recombinant SEL.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=153286Documentos Relacionados
- Synthesis of Enterotoxin by L-Forms of Staphylococcus aureus
- Identification and Characterization of Staphylococcal Enterotoxin Types G and I from Staphylococcus aureus
- Isolation and characterization of a plasmid involved with enterotoxin B production in Staphylococcus aureus.
- Detection of low-enterotoxin-producing Staphylococcus aureus strains.
- Enterotoxin B production by nongrowing cells of Staphylococcus aureus.