Brazilian Spotted Fever Prevention through a Nonlethal Capybara Population Control Strategy
AUTOR(ES)
Rosenfield, Derek Andrew
FONTE
Rev. Soc. Bras. Med. Trop.
DATA DE PUBLICAÇÃO
03/10/2019
RESUMO
Abstract INTRODUCTION: Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000 - 2018 >600 human deaths) involving synanthropic capybara as host. METHODS: We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine. RESULTS: The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas. CONCLUSIONS: We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.
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