Avaliação do efeito do tratamento periodontal convencional e associado à terapia antimicrobiana em pacientes com periodontite crônica sobre os níveis de Porphyromonas gingivalis e dos genótipos fimA II e IV no biofilme subgengival. / Evaluation of the effect of the conventional periodontal treatment and associated with antimicrobial therapy in chronic periodontitis patients on the levels of Porphyromonas gingivalis and fimA genotypes II and IV in the subgingival biofilm.

AUTOR(ES)
DATA DE PUBLICAÇÃO

2008

RESUMO

Porphyromonas gingivalis is one of the main mircrorganisms associate to periodontitis. The present study proposed to test the hypothesis that the colonization by different P.gingivalis genotypes fimA would lead to different results on periodontal treatment. Twenty chronic periodontitis patients, smokers, bearers of P. gingivalis was analyzed and divided in 2 groups: one group received mechanic periodontal treatment (SRP) and the other group received, besides SRP, antibiotic therapy (amoxicillin and metronidazole). The effect of treatment was appraised under clinical parameters, prevalence and subgingival levels of P. gingivalis and genotypes fimA II and fimA IV in quantitative study by Real time PCR, before and after 180 days of the treatment. Data suggest that SRP associated with systemic antibiotic administration is more efficient in reducing P. gingivalis levels than SRP only. No difference on periodontal treatment results was detected about the presence of fimA II or fimA IV genotypes related to other P.gingivalis genotypes.

ASSUNTO(S)

periodontal treatment porphyromonas gingivalis pcr real time tratamento periodontal genótipos subgingival biofilm genotypes porphyromonas gingivalis biofilmes subgengival pcr em tempo real

ACESSO AO ARTIGO

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