Avaliação de indicadores para complicações cardiovasculares em pacientes com anemia falciforme

AUTOR(ES)
DATA DE PUBLICAÇÃO

2006

RESUMO

INTRODUCTION: Sickle cell anemia is highly associated to cardiovascular co-morbidities, contributing to a decreased life expectancy and life quality in this group. The most important risk factors for cardiovascular disease include positive family history, hypertension, hypercholesterolemia, obesity, diabetes mellitus and smoking. OBJECTIVE: To evaluate cardiovascular risk factors among sickle cell anemia teenager patients as risk markers for forthcoming conditions aiming to extend longevity. METHODS: Thirty-five sickle cell anemia patients aged 13.82 2,41 years were followed. Body composition and BMI as well as clinical, biochemical and hematological parameters were analyzed. RESULTS: The average fat content in body composition reached 19.01 2.52, whereas BMD reached an average Z score of -2,26 1,78 (osteopenia), BMI = 17.48 2.42, glycemia = 75,08 12,78, systolic blood pressure = 10.51 1.35, diastolic blood pressure = 6.28 1.00 and CRP = 6.28 10.74. Mean hemoglobin levels were 8.92 1.60, indicating moderate-to-intense anemia. CONCLUSION: The parameters analyzed have not shown to be effective in predicting cardiovascular diseases among teenager sickle cell anemia patients. Nonetheless, the elevated mean values for CRP and VLDL are consistent with a higher risk for cardiovascular complications in this group.

ASSUNTO(S)

cardiologia densidade mineral óssea sistema cardiovascular - doenças bone mineral density fatores de risco cardiovascular proteína c reativa cardiovascular risk factors c-reactive protein anemia falciforme gordura corporal sickle cell anemia fat content

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