AvaliaÃÃo hepÃtica apÃs transplante de fÃgado: Estudo comparativo utilizando soluÃÃo de Belzer e Collins / Evaluation of the hepÃtica function after the liver transplant: comparative study using solution of Belzer and Collins

AUTOR(ES)
FONTE

IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia

DATA DE PUBLICAÇÃO

26/11/2008

RESUMO

The hepatic transplant is the standard treatment for terminal hepatic illness. With the refinement of the surgical technique, improvement of the effectiveness of the immunosuppressive drugs, the better knowledge of the reperfusion injury and the use of more physiological solutions of preservation, had a considerable increase of the survival of hepatic graft. The Collinsâ preservation solution used since 1969 , in renal transplant, is simplest and most economic preservation solution. The Belzerâs solution is used world wide and preserves hepatic graft for a longer period, although more expensive. The present study it compares 2 projects of hepatic perfusion using the Collins and Belzerâs solution. The difference between the two groups is that the Belzerâs solution perfused for the portal vein is substituted by the solution of Collins. At Walter CantÃdio Hospital of the Federal University of the Cearà 49 patients submitted to hepatic transplant of deceased donors graft were evaluated. The hepatic function after the transplant was evaluated through parameters AST, ALT, INR and Bilirubin in first and the seventh postoperative day. The time of cold ischemia was less than 10 hours in all the patients. There was no difference between the two groups in the analyzed parameters, except in the INR of the group where Collinsâ solution in the portal vein was perfused, which was greater in the 1 postoperative day. The two projects of hepatic preservation can be used with security, as the cold ischemia time is less than 10 hours, however, it had a reduction of the cost of the liver transplant in the group that used a lesser volume of the solution of Belzer.

ASSUNTO(S)

cirurgia transplante de fÃgado liver transplant organ preservation solutions funÃÃo hepÃtica

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