ASSOCIATION OF EPSTEIN-BARR VIRUS (EBV) BUT NOT HUMAN PAPILLOMAVIRUS (HPV) WITH GINGIVITIS AND/OR PERIODONTITIS IN TRANSPLANTED INDIVIDUALS

AUTOR(ES)

BAEZ, Camila Freze, SAVASSI-RIBAS, Flavia, ROCHA, Wilker Menezes da, ALMEIDA, Stéphanie G. S., GONÇALVES, Marianna T. V., GUIMARÃES, Maria Angelica A. M., CAVALCANTI, Silvia Maria B., VARELLA, Rafael B.

FONTE

Rev. Inst. Med. trop. S. Paulo

DATA DE PUBLICAÇÃO

11/07/2016

RESUMO

SUMMARY The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals.

Documentos Relacionados

• Epstein-Barr Virus (EBV) DNA in Sera of Patients with Primary EBV Infection
• Clonal propagation of Epstein-Barr virus (EBV) recombinants in EBV-negative Akata cells.
• In situ hibridization for Epstein-Barr virus (EBV) and Human Papiloma virus in drug-induced gingival overgrowth in renal transplantation patients
• Epstein-Barr virus (EBV) gene expression in EBV-positive peripheral T-cell lymphomas.
• Expression of Epstein-Barr virus (EBV) transcripts encoding homologues to important human proteins in diverse EBV associated diseases.