Associação entre densidade mineral óssea e status da vitamina D em mulheres idosas

AUTOR(ES)
FONTE

IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia

DATA DE PUBLICAÇÃO

10/05/2012

RESUMO

Vitamin D has a fundamental role in bone metabolism and skeletal integrity, and is also associated with the appearance of several diseases. Receptors for this vitamin are present in all tissues, which explains these associations. Decreased calcium absorption with advancing age is strongly related to declining vitamin D levels. Use of excess clothing, little exposure to sunlight, reduction of pro-vitamin D in the skin, diminished intake of vitamin D-rich foods, loss of mobility and institutionalization are factors relating to vitamin D deficiency. The aim of this study was to estimate the prevalence of hypovitaminosis D and identify the relationships between vitamin D status and bone mineral density (BMD) among 128 elderly women living in the Federal District, a region with constant incidence of sunlight. It was investigated the percentage body fat, parathormone (PTH) levels and serum and ionic calcium. The prevalence of hypovitaminosis D encountered was 73.95%. There was an association between BMD and vitamin D status, consistent with other studies, thus demonstrating that BMD is a good marker for vitamin D status among elderly women. An inverse relationship was suggested between PTH and vitamin D only in cases of vitamin D deficiency less than 20 ng/mL. The prevalence of hypovitaminosis D was significantly greater among elderly women with calcium levels outside of the normal range, although there was no significant relationship with abnormal ionic calcium levels. No association was found between percentage body fat and vitamin D, thus diverging from other authors reports. Our results are consistent with descriptions from regions with little solar radiation. Further studies are needed in order to investigate the association between hypovitaminosis D and the multiple conditions that favor the onset of bone loss, with the aim of identifying groups at greater risk, for whom dietary supplementation of vitamin D should be recommended.

ASSUNTO(S)

vitamina d mulheres idosas osteoporose gerontologia ciencias da saude hypovitaminosis d bone mineral density parathormone body fat elderly women

ACESSO AO ARTIGO

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