AMINO SUGARS IN L FORMS OF BACTERIA AND PLEUROPNEUMONIA-LIKE ORGANISMS1

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Sharp, John T. (Harvard Medical School, Boston, Mass.). Amino sugars in L forms of bacteria and pleuropneumonia-like organisms. J. Bacteriol. 86:692–701. 1963.—Studies of several bacterial L forms and their parent bacteria have revealed similar amino sugars in the two forms of microorganisms, with the exception that muramic acid was absent from the streptococcal and staphylococcal L forms. In contrast, muramic acid was found in a Proteus L form. Some of the properties of the muramic acid component in the Proteus L form are described. The solubility of this material was observed to be very different in the L form as compared with the bacterium. Some implications of this observation are discussed. Two strains of pleuropneumonia-like organisms did not contain muramic acid.

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