Altered Nucleic Acids of Antibody-Forming Tissues*
AUTOR(ES)
Little, J. Russell
RESUMO
RNA·DNA hybridization experiments suggest differences between the DNA from the liver and spleen of the same animal (rabbit) and between the RNAs from lymph nodes stimulated by different antigens. A larger proportion of spleen DNA than of liver DNA was complementary to the RNA isolated from antigen-stimulated lymph nodes. No difference between liver and spleen DNA was observed in hybrids formed with RNA from lymph nodes of nonimmune animals. This suggests the presence of unique or redundant genes coding for immunoglobulin polypeptide chains in antibody-forming cells.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=283352Documentos Relacionados
- RELATIVE ANTIBODY-FORMING CAPACITY OF SPLEEN CELLS AS A FUNCTION OF AGE
- Modified hemolytic plaque technique for the detection of bluetongue virus antibody-forming cells.
- Detection of virus-specific antibody-forming cells of mice immunized with Newcastle disease virus.
- Similar Idiotypes in Antibody-Forming Cells and in Cells Synthesizing Immunoglobulins Without Detectable Antibody Function
- A simple device for counting Jerne's plates to detect haemolytic antibody-forming cells.
