Acute coronary thrombosis in a patient with diabetes and severe hyperglycemia

AUTOR(ES)

Roberts, Jason D

FONTE

Pulsus Group Inc

RESUMO

The pathophysiological processes responsible for acute coronary events in diabetic patients, in addition to the conventional factors associated with plaque rupture, include an enhanced prothrombotic state. This enhanced prothrombotic state results from multiple abnormalities of the coagulation system including platelet activation, impaired fibrinolysis and increased activity of the coagulation cascade. Studies have also demonstrated that severe hyperglycemia can result in an exacerbation of the underlying prothrombotic state, indicating that patients with extreme hyperglycemia are subject to an even greater thrombotic risk. The present case illustrates the thrombotic hazards associated with severe hyperglycemia.

Documentos Relacionados

• Acute Coronary Syndrome in a Patient With Single-Vessel Coronary Artery: Case Report
• Preoperative laser therapy in a patient with resectable bronchogenic carcinoma and severe coronary artery disease.
• Pathological concepts in acute coronary thrombosis: relevance to treatment.
• Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi.
• Diabetes worsens prognosis in acute coronary syndrome