Abnormal anal cytology risk in women with known genital squamous intraepithelial lesion
AUTOR(ES)
do Socorro Nobre, Maria, Jacyntho, Claudia Marcia, Eleutério Jr, José, Giraldo, Paulo César, Gonçalves, Ana Katherine
FONTE
Braz J Infect Dis
DATA DE PUBLICAÇÃO
2016-06
RESUMO
Abstract The purpose of this study was to assess the risk of abnormal anal cytology in women with known genital squamous intraepithelial lesion. This study evaluated 200 women with and without genital squamous intraepithelial lesion who were recruited for anal Pap smears. Women who had abnormal results on equally or over atypical squamous cells of undetermined significance were classified as having abnormal anal cytology. A multiple logistic regression analysis (stepwise) was performed to identify the risk for developing abnormal anal cytology. Data were analyzed using the SPSS 20.0 program. The average age was 41.09 (±12.64). Of the total participants, 75.5% did not practice anal sex, 91% did not have HPV-infected partners, 92% did not have any anal pathology, and 68.5% did not have anal bleeding. More than half (57.5%) had genital SIL and a significant number developed abnormal anal cytology: 13% in the total sample and 17.4% in women with genital SIL. A significant association was observed between genital squamous intraepithelial lesion and anal squamous intraepithelial lesion (PR = 2.46; p = 0.03). In the logistic regression model, women having genital intraepithelial lesion were more likely to have abnormal anal Pap smear (aPR = 2.81; p = 0.02). This report shows that women with genital squamous intraepithelial lesion must be more closely screened for anal cancer.
Documentos Relacionados
- Anal High-risk HPV and Liquid-based Cytology of Immunocompetent Brazilian Women with Genital High-risk HPV
- Cytology-based Screening for Anal Intraepithelial Neoplasia in Immunocompetent Brazilian Women with a History of High-Grade Cervical Intraepithelial Neoplasia or Cancer
- Management of Anal Squamous Intraepithelial Lesions
- Cervical glandular atypia associated with squamous intraepithelial neoplasia: a premalignant lesion?
- Cervical intraepithelial neoplasia in women presenting with external genital warts