A Trial of Oil-Adjuvant Influenza Vaccine in a Non-Epidemic Season

AUTOR(ES)

Howell, R. W.

RESUMO

In the autumn of 1963, 1,679 employees at two U.K.A.E.A. establishments were inoculated with a single dose (0·25 ml.) of polyvalent oil-adjuvant influenza vaccine. In a non-epidemic winter, no significant improvement in certified sickness absence could be demonstrated in the vaccinated group when compared with a randomly selected uninoculated group. In particular, no real protection was shown, in those vaccinated, against influenza and acute upper respiratory tract infections. Once respiratory sickness had occurred the vaccine showed no significant effect on the length of sickness absence.

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