A noninflammatory pathway for pregnancy loss: innate immune activation?

AUTOR(ES)

Salmon, Jane E.

FONTE

American Society for Clinical Investigation

RESUMO

Although the mechanisms of immune-mediated pregnancy loss are unknown, investigations are currently focused on mediators of immune activation and tissue injury at the maternal-fetal interface. A new study, however, demonstrates that systemic inflammatory mediators can induce pregnancy failure in a different way, by inhibiting ovarian hormone production, and identifies links between the immune and reproductive endocrine systems.

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