A New Actinomycin Complex Produced by a Micromonospora Species: Fermentation, Isolation, and Characterization
AUTOR(ES)
Wagman, G. H
RESUMO
A species of Micromonospora, Micromonospora floridensis NRRL 8020, has been found to produce an actinomycin complex consisting of at least 25 active components. After solvent extraction of the complex, separation of the individual components was carried out by preparative thin-layer chromatography. Hydrolysis and subsequent electrophoretic and chromatographic identification of the amino acid content of each of the isolated components have shown differences from known actinomycins, and the probability exists that these contain a number of amino or imino acids not previously found in other members of this group of antibiotics.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=429553Documentos Relacionados
- Antibiotic G-418, a New Micromonospora-Produced Aminoglycoside with Activity Against Protozoa and Helminths: Fermentation, Isolation, and Preliminary Characterization
- Screening, Fermentation, Isolation, and Characterization of Trypanomycin, a New Antibiotic
- Fermentation, Isolation, and Antitumor Activity of Sterigmatocystins
- Agar-Like Polysaccharide Produced by a Pseudomonas Species: Production and Basic Properties
- Cloning, isolation, and characterization of replication regions of complex plasmid genomes.
