Apolipoproteins E
Mostrando 1-12 de 62 artigos, teses e dissertações.
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1. Associação de lipoproteína de alta densidade e variantes genéticas da apolipoproteína E com degeneração macular relacionada à idade
Objetivo: Este estudo teve como objetivo avaliar a associação de degeneração macular relacionada à idade (DMRI) com variantes de alipoproteína E (APOE) e perfil lipídico sérico, incluindo níveis séricos de colesterol total (TC) e frações de proteínas relacionadas a receptor de LDL (LDLc) e HDL colesterol (HDLc), e triglicérides (TG). Métodos:
Arq. Bras. Oftalmol.. Publicado em: 2015-04
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2. UTILIDADE CLÍNICA DE DIFERENTES MEDIDAS DE LIPÍDIOS E ATIVIDADE INFLAMATÓRIA NA DETECÇÃO DE DOENÇA ARTERIAL CORONARIANA / CLINICAL UTILITY OF DIFFERENT MEASURES OF LIPID AND INFLAMMATORY ACTIVITY IN THE DETECTION OF CORONARY ARTERY DISEASE
Introdução: A doença arterial coronariana constitui uma das principais causas de mortalidade no mundo. As apolipoproteínas surgem como um novo parâmetro, mais sensíveis e específicas, além de não necessitar de jejum de 12 horas para coleta de sangue. A proteína C reativa é o marcador inflamatório mais estudado, sua presença já foi constatada em
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/11/2011
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3. Poliformismos do gene da proteína príon celular em pacientes com doença de Alzheimer / Prion protein gene polymorphism in Alzheimers disease
INTRODUÇÃO: Os polimorfismos do gene da proteína priônica (PRNP) podem estar associados a doenças neurológicas não priônicas. Estudos em pacientes com doença de Alzheimer (DA) apontam para possível associação entre os polimorfismos do códon 129 do PRNP e DA. Essa associação não foi estudada na população brasileira. Neste estudo, descrevemos
Publicado em: 2011
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4. Efeitos do polimorfismo T-786C do gene da óxido nítrico sintase endotelial (eNOS) e/ou da atorvastatina sobre parâmetros do metabolismo lipídico em adultos assintmáticos / Effects of the polymorphism T-786C of endothelial nitric oxide synthase (eNOS) gene and/or atorvastatin on parameters of lipid metabolism in asymptomatic adults
Nitric oxide (NO) is produced in the vascular endothelium by endothelial nitric oxide synthase (eNOS), an enzyme negatively regulated by the presence of the T-786C polymorphism, leading to endothelial dysfunction. High-density lipoproteins (HDL) have well-established anti-atherogenic functions, for example mechanisms that enhance eNOS activity. Statins are d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/08/2010
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5. Seriam as apolipoproteinas A e B mais eficientes do que as lipoproteinas na investigacao de risco de doenca arterial coronariana obstrutiva? / Are apolipoproteins A and B better than lipoproteins for assessing risk of obstructive coronary heart disease?
Objective – To evaluate whether apolipoproteins A-I (Apo A-I) and B (Apo B) have, higher ensitivity (SN), specificity (SP) and positive predictive value (PPV) than lipoproteins (LP), total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL), and triglycerides (TGL) in assessing the risk of co
Publicado em: 2010
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6. Purification, partial characterization and role in lipid transport to developing oocytes of a novel lipophorin from the cowpea weevil, Callosobruchus maculatus
Lipid transport in arthropods is achieved by highly specialized lipoproteins, which resemble those described in vertebrate blood. Here we describe purification and characterization of the lipid-apolipoprotein complex, lipophorin (Lp), from adults and larvae of the cowpea weevil Callosobruchus maculatus. We also describe the Lp-mediated lipid transfer to deve
Brazilian Journal of Medical and Biological Research. Publicado em: 17/12/2007
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7. The beta-chemokines MIP-1alpha and RANTES and lipoprotein metabolism in HIV-infected brazilian patients
HIV patients are predisposed to the development of hypertriglyceridemia and hypercholesterolemia as a result of both viral infection and HIV infection therapy, especially the protease inhibitors. Chemokines and cytokines are present at sites of inflammation and can influence the nature of the inflammatory response in atherosclerosis. We investigated the corr
Brazilian Journal of Infectious Diseases. Publicado em: 2005-08
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8. APOA1/C3/A4 gene cluster variability and lipid levels in Brazilian children
Genetic studies have suggested that polymorphisms of genes coding for apolipoproteins are significant determinants of serum lipoprotein and lipid levels in adults. However, only a few studies have investigated the association of these polymorphisms in children. Therefore, in the present investigation we studied the distribution of APOA1 -75 G>A, +83 C>T, APO
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-04
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9. Polimorfismo da apolipoproteína E nos familiares em primeiro grau de pacientes com doença de alzheimer familial ou esporádica.
A apolipoproteína E (apo E) é reconhecida como fator de risco para Doença de Alzheimer (DA) em várias populações. Entretanto, permanece incerta a associação entre polimorfismo da apo E, caracterizado pelos alelos ε2, ε3 e ε4 e DA na população brasileira, e sua prevalência em familiares de pacientes com a doença. Este estudo teve co
Publicado em: 2003
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10. Eggplant (Solanum melongena) infusion has a modest and transitory effect on hypercholesterolemic subjects
Eggplant (Solanum melongena) is consumed extensively in Brazil. It has been believed that infusion of a powdered preparation of the fruit may reduce serum cholesterol. However, there are few documented reports on its effects on cholesterol metabolism and its possible hypocholesterolemic effect has not been proved by well-controlled studies. The aim of the pr
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-09
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11. Zymosan phagocytosis by mouse peritoneal macrophages is increased by apoHDL- and not by intact HDL-covered particles
The uptake of lipids and lipoprotein particles by macrophages undergoes phagocytic activation and the formation of foam cells are key events in atherosclerosis. In this study we determined how intact high density lipoproteins (HDL) and apolipoproteins-HDL (removal of the lipid component from HDL, i.e., apoHDL) influence the phagocytosis of zymosan by mouse p
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-03
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12. Perfis sericos lipidico, apoproteico e lipoproteico de pacientes portadores do virus da imunodeficiencia adquirida
Treatment with highly active anti-retrovkal therapy drugs (HAART) has resulted in decrease of the viralload of human immunodeficiency virus (IDV) until its negativatio~ with concomitant rebuilding of the immune system. Potency and effectiveness of anti-retroviral therapies of high activity increase the life expectation of mv infected patients. However, resul
Publicado em: 2000