Antiretroviral
Mostrando 13-24 de 1430 artigos, teses e dissertações.
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13. Osteopenia and osteoporosis among treatment-experienced people living with HIV
Abstract Introduction Life expectancy of people living with human immunodeficiency (PLHIV) has increased mainly due to the accessibility and effectiveness of antiretroviral therapy (ART). However, adverse effects from long-term use of antiretrovirals, and the physiological changes associated with aging, may compromise the quality of life of PLHIV, in additi
Braz J Infect Dis. Publicado em: 2020-08
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14. Real-world evidence in antiretroviral therapy: drug safety data
Resumo Os tumores de hipófise representam aproximadamente 15% de todos os tumores cerebrais e dependendo do tamanho, pressionam o quiasma óptico, resultando em comprometimento da função visual que se manifesta como defeitos no campo visual, diminuição da acuidade visual e da visão das cores. O objetivo do presente estudo foi relatar um caso de macroad
Braz J Infect Dis. Publicado em: 2020-06
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15. Deep impact of COVID-19 in the healthcare of Latin America: the case of Brazil
ABSTRACT Background: Latent HIV-1 is a major hurdle in obtaining HIV-1 sustained virological remission (SVR). Here we explored histone deacetylation inhibition property of nicotinamide (NAM; n = 17) for the first time in comparison to a combination of methyltransferase inhibitors (MTIs; Chaetocin and BIX01294; n = 25) to reactivate latent HIV ex vivo in CD8
Braz J Infect Dis. Publicado em: 2020-04
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16. Nicotinamide activates latent HIV-1 ex vivo in ART suppressed individuals, revealing higher potency than the association of two methyltransferase inhibitors, chaetocin and BIX01294
ABSTRACT Background: Latent HIV-1 is a major hurdle in obtaining HIV-1 sustained virological remission (SVR). Here we explored histone deacetylation inhibition property of nicotinamide (NAM; n = 17) for the first time in comparison to a combination of methyltransferase inhibitors (MTIs; Chaetocin and BIX01294; n = 25) to reactivate latent HIV ex vivo in CD8
Braz J Infect Dis. Publicado em: 2020-04
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17. Profile of drug-drug interactions and impact on the effectiveness of antiretroviral therapy among patients living with HIV followed at an Infectious Diseases Referral Center in Belo Horizonte, Brazil
ABSTRACT HIV infection may be considered a chronic condition for people living with HIV with access to antiretrovirals and this has effectively increased survival. Moreover, this has also facilitated the emergence of other comorbidities increasing the risk for drug-drug interactions and polypharmacy. The profile of these interactions as well as their consequ
Braz J Infect Dis. Publicado em: 2020-04
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18. Factors related to adherence to antiretroviral treatment in a specialized care facility
RESUMO O objetivo deste estudo foi verificar os níveis de adesão ao tratamento antirretroviral e os fatores associados a ela. Trata-se de um estudo descritivo de delineamento transversal baseado em levantamento de prontuários. Para tanto, foi utilizado um questionário composto de informações sociodemográficas e clínicas de pacientes com idade entre 1
Rev. Assoc. Med. Bras.. Publicado em: 2020-03
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19. Síndrome lipodistrófica do HIV e seus fatores associados: um estudo em um hospital universitário
Resumo O uso de antirretroviral aumentou a sobrevida dos portadores do HIV, porém pode acarretar efeitos colaterais, como a síndrome lipodistrófica. O objetivo deste artigo é identificar a frequência da síndrome lipodistrófica e seus fatores associados em pacientes portadores do HIV em uso de terapia antiretroviral. Estudo transversal com pacientes ac
Ciênc. saúde coletiva. Publicado em: 2020-03
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20. Factors associated to modification of first-line antiretroviral therapy due to adverse events in people living with HIV/AIDS
ABSTRACT Antiretroviral therapy (ART) has modified the outcome of patients with HIV infection, providing virological control and reducing mortality. However, there are several reasons as to why patients may discontinue their antiretroviral therapy, with adverse events being one of the main reasons reported in the literature. This is a case-control nested in
Braz J Infect Dis. Publicado em: 2020-02
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21. Development and validation of a simple and rapid way to generate low volume of plasma to be used in point-of-care HIV virus load technologies
ABSTRACT A new point-of-care HIV viral load, mPIMA HIV-1/2 VL, Abbott, USA, has been recently developed. This point-of-care viral load requires no skilled person to run and uses a small plasma volume (50 µL). However, obtaining 50 µL of plasma can be a challenge in limited resource settings. We validated a simple and easy method to obtain enough amount of
Braz J Infect Dis. Publicado em: 2020-02
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22. Kaposi’s sarcoma in a HIV-positive patient: an exuberant and widespread case report in the Amazon
ABSTRACT A 37-year-old male patient, Fitzpatrick skin phototype IV, a student living in Belem, Amazon region, in 2015 had a confirmed diagnosis of acquired immunodeficiency virus (HIV) infection, but did not initiate antiretroviral treatment at his own option. Three years after the diagnosis, erythematous maculae appeared on the dorsum of the nose with rapid
Rev. Inst. Med. trop. S. Paulo. Publicado em: 17/01/2020
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23. Correlation of Low CD4+ Counts with High Dental Caries Prevalence in Children Living with Perinatal HIV/AIDS Undergoing Antiretroviral Therapy
Abstract Objective: To investigate the correlation Cluster of Differentiation 4+ (CD4+) counts with a high prevalence of dental caries in Children Living with Perinatal Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (CLWPHA). Material and Methods: An analytical observational research with a cross-sectional design was conducted at Tertiary
Pesqui. Bras. Odontopediatria Clín. Integr.. Publicado em: 13/01/2020
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24. HIV-related nephropathy: new aspects of an old paradigm
RESUMO O panorama da infecção pelo vírus da imunodeficiência humana (HIV) vem sofrendo alterações nos últimos anos, tanto em relação ao entendimento da infecção pelo HIV quanto aos tratamentos disponíveis. Como resultado, a doença, que antes estava associada a alta morbimortalidade, é agora considerada uma doença crônica que pode ser controla
Rev. Assoc. Med. Bras.. Publicado em: 13/01/2020