Antigenic Variation
Mostrando 1-12 de 458 artigos, teses e dissertações.
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1. Immunoproteomics of Plasmodium falciparum-infected red blood cell membrane fractions
BACKGROUND The surface of infected red blood cells (iRBCs) has been widely investigated because of the molecular complexity and pathogenesis mechanisms involved. Asymptomatic individuals are important in the field because they can perpetuate transmission as natural reservoirs and present a challenge for diagnosing malaria because of their low levels of circ
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-12
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2. Partial VP1 sequencing of Brazilian infectious bursal disease virus strains
Infectious bursal disease virus (IBDV) is classified according to the antigenicity and virulence into classical virulent (cv), very virulent (vv), and antigenic variant strains. The molecular basis for the IBDV antigenic variation is well established and is associated to the capsid protein, VP2 (gene VP2 of segment A), whereas both VP2 and the RNA-dependent
Braz. J. Microbiol.. Publicado em: 2012-09
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3. Coping with genetic diversity: the contribution of pathogen and human genomics to modern vaccinology
Vaccine development faces major difficulties partly because of genetic variation in both infectious organisms and humans. This causes antigenic variation in infectious agents and a high interindividual variability in the human response to the vaccine. The exponential growth of genome sequence information has induced a shift from conventional culture-based to
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-05
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4. A preliminary survey of M. hyopneumoniae virulence factors based on comparative genomic analysis
Mycoplasma hyopneumoniae is the etiological agent of porcine enzootic pneumonia (PEP), a major problem for the pig industry. The mechanisms of M. hyopneumoniae pathogenicity allow to predict the existence of several classes of virulence factors, whose study has been essentially restricted to the characterization of adhesion-related and major antigenic protei
Publicado em: 2010
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5. Identificação de novos antígenos flagelares e variação de fase em amostras de Escherichia coli isoladas de animais e alimentos / Identification of new flagellar antigen and phase variation in Escherichia coli isolated from animals and food
Escherichia coli é um membro comensal da microbiota de animais, porém podem causar doenças desde diarréias até sepses. A caracterização dos seus antígenos de superfície O (somático) e H (flagelar) auxilia na determinação de linhagens patogênicas dentro da espécie. Contudo, algumas bactérias não expressam flagelo in vitro, demonstrado que a am
Publicado em: 2010
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6. CaracterizaÃÃo molecular dos vÃrus sincicial respiratÃrio humano circulantes em Fortaleza-Cearà durante cinco perÃodos epidÃmicos consecutivos (2004-2008). / Molecular characterization of human repiratÃrio syncytial virus circulating in Fortaleza, Ceara during five consecutive epidemic periods (2004-2008).
vÃrus sincicial respiratÃrio humano (VSRh) à o agente viral mais freqÃentemente relacionado a infecÃÃes do trato respiratÃrio inferior em crianÃas menores de dois anos de idade. O VSRh à caracterizado antigenicamente em dois grupos: A e B, e cada grupo apresenta vÃrios subgrupos. A glicoproteÃna G à a principal responsÃvel pela a variaÃÃo anti
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/12/2009
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7. Merozoite surface protein 2 allelic variation influences the specific antibody response during acute malaria in individuals from a Brazilian endemic area
The antibody response to Plasmodium falciparum parasites of naturally infected population is critical to elucidate the role of polymorphic alleles in malaria. Thus, we evaluated the impact of antigenic diversity of repetitive and family dimorphic domains of the merozoite surface protein 2 (MSP-2) on immune response of 96 individuals living in Peixoto de Azev
Memórias do Instituto Oswaldo Cruz. Publicado em: 17/05/2007
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8. A preliminary survey of M. hyopneumoniae virulence factors based on comparative genomic analysis
Mycoplasma hyopneumoniae is the etiological agent of porcine enzootic pneumonia (PEP), a major problem for the pig industry. The mechanisms of M. hyopneumoniae pathogenicity allow to predict the existence of several classes of virulence factors, whose study has been essentially restricted to the characterization of adhesion-related and major antigenic protei
Genetics and Molecular Biology. Publicado em: 2007
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9. Avaliação da imunidade protetora de uma cepa atenuada de Eimeria acervulina, em galinhas (Gallus gallus), apos desafios com as cepas parentais homologa e duas heterologas
Evaluation of protective immunity produced by immunization of chickens (Gallus gallus) with the attenuated tine "Cu" of Eimeria acervulina after challenge with its homologous and two heterologous strains "PePa" e "I" was performed. Seven day old White Leghorn SPP (Specific Pathogen Pree) chickens were used for experiments. Each bird received a dose of lxl03
Publicado em: 2003
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10. Frequency of Pilin Antigenic Variation in Neisseria gonorrhoeae
Variation of the pilus of Neisseria gonorrhoeae occurs by the recombination of silent pilin DNA sequences into the pilin expression locus. We have developed a quantitative, competitive reverse transcription-PCR assay which measures the frequency of pilin antigenic variation independently of changes in gonococcal colony morphology and have determined this fre
American Society for Microbiology.
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11. Antigenic variation in Plasmodium falciparum.
Antigenic variation of infectious organisms is a major factor in evasion of the host immune response. However, there has been no definitive demonstration of this phenomenon in the malaria parasite Plasmodium falciparum. In this study, cloned parasites were examined serologically and biochemically for the expression of erythrocyte surface antigens. A cloned l
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12. Phase and Antigenic Variation in Bacteria
Phase and antigenic variation result in a heterogenic phenotype of a clonal bacterial population, in which individual cells either express the phase-variable protein(s) or not, or express one of multiple antigenic forms of the protein, respectively. This form of regulation has been identified mainly, but by no means exclusively, for a wide variety of surface
American Society for Microbiology.